Electrospun TiO 2 Nanofiber‐Based Cell Capture Assay for Detecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients
2012; Volume: 24; Issue: 20 Linguagem: Inglês
10.1002/adma.201200155
ISSN1521-4095
AutoresNangang Zhang, Yuliang Deng, Qidong Tai, Boran Cheng, Libo Zhao, Qinglin Shen, Rongxiang He, Longye Hong, Wei Liu, Shishang Guo, Kan Liu, Hsian‐Rong Tseng, Bin Xiong, Xingzhong Zhao,
Tópico(s)Electrospun Nanofibers in Biomedical Applications
ResumoA nanostructured platform that combines electrospun TiO2 nanofibers (TiNFs)-deposited substrate and cell-capture agent realizes significant capture of circulating tumor cells (CTCs). The enhanced local topographic interactions between the horizontally packed TiNFs deposited substrates and extracellular matrix scaffolds, in addition to anti-EpCAM/EpCAM biological recognition, contributes to the significantly enhanced capture efficiency compared to flat surfaces. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Referência(s)