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Magnetic Resonance Imaging of the Cerebral Aqueduct Signal Intensity Time Curves Demonstrated by Fast Acquisition With Multiple Excitation (FAME)

1989; Lippincott Williams & Wilkins; Volume: 24; Issue: 11 Linguagem: Inglês

10.1097/00004424-198911000-00004

1536-0210

J. H. W. Van Den Hout, Chris J.G. Bakker, Willem P.Th.M. Mali, Pim van Dijk, Joyce Faber, Michiel A. M. Feldberg, R. H. J. M. Gooskens, T. D. Witkamp,

Functional Brain Connectivity Studies

Using cardiac-gated fast acquisition with multiple excitation (FAME), time curves of the cerebral aqueduct signals were derived in 19 healthy volunteers and 14 patients. A mean curve of the normal subjects was determined during systole. A relatively stable point of time was found at 270 msec after the R-wave supposed to be the reversal of the flow of cerebralspinal fluid in the aqueduct. Different curves were noticed in complete aqueductal obstruction (n=2); in other pathologic states, such as cerebral tumor (n=3), normal pressure hydrocephalus (n=3), and brain atrophy (n=1), no different signal time curves were observed. Parameters such as aqueduct diameter, cerebro-spinal fluid volume and brain compliance are probably other important factors in aqueduct liquor flow.