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Subacute Combined Degeneration of the Spinal Cord Concomitant with Gastric Cancer

2006; The Japanese Society of Internal Medicine; Volume: 45; Issue: 14 Linguagem: Inglês

10.2169/internalmedicine.45.1811

1349-7235

Ayako Hirata, Nobuatsu Nomoto, Shingo Konno, Hiroshi Nakazora, Hideki Sugimoto, Hiroshi Nemoto, Teruyuki Kurihara, Nobuo Wakata,

Restless Legs Syndrome Research

We report a rare case of subacute combined degeneration of the spinal cord concomitant with gastric cancer. A 67-year-old man was admitted because of posterior column symptoms, pyramidal tract sign and peripheral neuropathy with severe hyperchromic anemia. He was treated with mecobalamin 1 mg IM, after which his anemia and neurological signs recovered. He was diagnosed as having subacute combined degeneration with pernicious anemia. Subsequent stomach biopsy revealed gastric cancer, and the patient underwent gastrectomy. It is a well known association that chronic atrophic gastritis is associated with gastric cancer or subacute combined degeneration. Our findings suggest that in this case subacute combined degeneration and gastric cancer are independent of each other; rather, both resulted from chronic atrophic gastritis.