Atypical antipsychotics in the elderly with Parkinson disease and the “black box” warning
2006; Lippincott Williams & Wilkins; Volume: 67; Issue: 4 Linguagem: Inglês
10.1212/01.wnl.0000229933.91780.67
ISSN1526-632X
Autores Tópico(s)Health Systems, Economic Evaluations, Quality of Life
ResumoIn the last 2 years, regulatory agencies in the UK and the USA have made recommendations and "black box" warnings, regarding the use of atypical antipsychotic drugs in the elderly because of a purported increase in risk of stroke and death in elderly demented patients. These advisories did not address the adverse effects of "typical" (first-generation) antipsychotics. In this article, the author reviews the history of these developments and raises issues that still need to be addressed by the neurologic community.
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