Artigo Acesso aberto Produção Nacional Revisado por pares

Reações intramoleculares como modelos não miméticos de catálise enzimática

1997; Brazilian Chemical Society; Volume: 20; Issue: 6 Linguagem: Inglês

10.1590/s0100-40421997000600011

ISSN

1678-7064

Autores

José C. Gesser, Santiago F. Yunes, Rosilene Maria Clementin, Faruk Nome,

Tópico(s)

Enzyme Production and Characterization

Resumo

This review gives a critical idea on the importance of intramolecular reactions as models for enzymatic catalysis.Intramolecular lactonizations, ester and amide hydrolysis studies result in theories which try to explain the difference between intermolecular, intramolecular and enzyme reactions and rationalize the enhancement promoted by these biological catalyst.

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