Catalytic Deprotection of Acetals in Basic Solution with a Self‐Assembled Supramolecular “Nanozyme”
2007; Wiley; Volume: 46; Issue: 45 Linguagem: Inglês
10.1002/anie.200703371
ISSN1521-3773
AutoresMichael D. Pluth, Robert G. Bergman, Kenneth N. Raymond,
Tópico(s)Chemical Synthesis and Analysis
ResumoAngewandte Chemie International EditionVolume 46, Issue 45 p. 8587-8589 Communication Catalytic Deprotection of Acetals in Basic Solution with a Self-Assembled Supramolecular “Nanozyme”† Michael D. Pluth, Michael D. Pluth Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this authorRobert G. Bergman Prof., Robert G. Bergman Prof. rbergman@cchem.berkeley.edu Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this authorKenneth N. Raymond Prof., Kenneth N. Raymond Prof. raymond@socrates.berkeley.edu Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this author Michael D. Pluth, Michael D. Pluth Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this authorRobert G. Bergman Prof., Robert G. Bergman Prof. rbergman@cchem.berkeley.edu Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this authorKenneth N. Raymond Prof., Kenneth N. Raymond Prof. raymond@socrates.berkeley.edu Department of Chemistry, University of California, Berkeley, CA 94720–1460, USA, Fax: (+1) 510-642-7714 (Bergman), Fax: (+1) 510-486-5283 (Raymond) http://chem.berkeley.edu/people/faculty/bergman/bergman.htmlhttp://chem.berkeley.edu/people/faculty/raymond/raymond.htmlSearch for more papers by this author First published: 08 November 2007 https://doi.org/10.1002/anie.200703371Citations: 105 † We gratefully acknowledge financial support from the Director, Office of Science, Office of Basic Energy Sciences, and the Division of Chemical Sciences, Geosciences, and Biosciences of the US Department of Energy at LBNL under Contract No. DE-AC02-05CH11231 and an NSF predoctoral fellowship to M.D.P. We thank Dr. D. Leung, Dr. S. Biros, Dr. M. Seitz, and C. Hastings for helpful discussions. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Changing on the inside: Acetals are a commonly used protecting groups for aldehydes and ketones in organic synthesis because of their ease of installation and resistance to cleavage in neutral or basic solution. A self-assembled supramolecular assembly has been shown to catalyze the hydrolysis of acetals and ketals in basic solution (see scheme). Citing Literature Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description anie_200703371_sm_miscellaneous_information.pdf68.3 KB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume46, Issue45November 19, 2007Pages 8587-8589 RelatedInformation
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