Relation between Total Serum IgE Levels and IgE Antibody Production in Rats
1979; Karger Publishers; Volume: 58; Issue: 3 Linguagem: Inglês
10.1159/000232212
ISSN1423-0097
AutoresRuben Pauwels, Hervé Bazin, B. Platteau, M. Van Der Straeten,
Tópico(s)Monoclonal and Polyclonal Antibodies Research
ResumoFive different rat strains were immunized with 100 μg ovalbumin and 1 mg Al (OH)<sub>3</sub>. A good correlation was found between the total serum IgE level of a rat strain before immunization and the IgE antibody production. Good IgE antibody-producing strains had high total serum IgE levels and vice versa. A discordance between the evolution of the total serum IgE level after immunization and the changes in IgE antibody level was found in all strains.
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