Relationship between the extent of the hypoperfused zone of the myocardium and the occurrence of ventricular fibrillation
1983; Elsevier BV; Volume: 105; Issue: 6 Linguagem: Inglês
10.1016/0002-8703(83)90390-3
ISSN1097-6744
AutoresTakao Endo, Lair G.T. Ribeiro, Wai-man Cheung, Duarte B. Faria, Michael Petranto, Peter R. Maroko,
Tópico(s)Chemical Thermodynamics and Molecular Structure
ResumoVentricular fibrillation and subsequent death frequently occur so soon after coronary artery occlusion that infarct size cannot be determined; thus the systematic study of their relationship is impossible. Recently, however, a technique has been developed that permits the assessment, in vivo, of the extent of the myocardial hypoperfused zone (HZ). Accordingly, in 55 open-chest dogs, 99mTc-labeled (8 mCi) albumin microspheres (15 μm in diameter) were injected into the left atrium 1 minute after coronary artery occlusion. The zone of hypoperfusion was analyzed in 28 dogs that had ventricular fibrillation (group A) and 27 dogs that had no ventricular fibrillation (group B). In group B, the HZ was 26.3 ± 1.7% of the left ventricle vs 31.6 ± 1.3% of the left ventricle in group A (p < 0.05), showing that ventricular fibrillation occurred in dogs with larger zones of hypoperfusion.
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