Artigo Revisado por pares

A universal biosensor for multiplex DNA detection based on hairpin probe assisted cascade signal amplification

2013; Royal Society of Chemistry; Volume: 49; Issue: 45 Linguagem: Inglês

10.1039/c3cc41941j

ISSN

1364-548X

Autores

Jie Liu, Lingbo Chen, Puchang Lie, Boying Dun, Lingwen Zeng,

Tópico(s)

Advanced Biosensing Techniques and Applications

Resumo

A hairpin DNA probe mediated cascade signal amplification method was developed for visual and rapid DNA analysis with a detection limit of 100 aM. The implementation of tag/anti-tag DNA and gold nanoparticle reporters permits a universal platform for multiplex genotyping without instrumentation.

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