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From skin dendritic cells to a simplified classification of human and mouse dendritic cell subsets

2010; Wiley; Volume: 40; Issue: 8 Linguagem: Inglês

10.1002/eji.201040498

1521-4141

Martin Guilliams, Sandrine Henri, Samira Tamoutounour, Laurence Ardouin, Isabelle Schwartz‐Cornil, Marc Dalod, Bernard Malissen,

Immune Cell Function and Interaction

Abstract Recent studies have identified several DC subsets within the mouse skin and showed that functional specialization exists among them. This Viewpoint summarizes recent data on functional specialization of skin DC subsets and integrates this knowledge into a unifying DC classification that emphasizes the similarities between the DC subsets found in both lymphoid and nonlymphoid tissues of several mammalian species.