Editorial Revisado por pares

Anemia of Chronic Disease: A Misnomer

1991; American College of Physicians; Volume: 115; Issue: 7 Linguagem: Inglês

10.7326/0003-4819-115-7-572

ISSN

1539-3704

Autores

Robert Schilling,

Tópico(s)

Iron Metabolism and Disorders

Resumo

Editorials1 October 1991Anemia of Chronic Disease: A MisnomerRobert F. Schilling, MDRobert F. Schilling, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-7-572 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe anemia that results from long- or short-term inflammation is commonly referred to as the anemia of chronic diseases or disorders (1-4). Use of this terminology is a mistake and leads to confusion in many nonhematologists. Others share my view. Hansen (5) wrote, "It is quite obvious that the name anaemia of chronic disorders is singularly inappropriate. . .". Many chronic diseases are not accompanied by anemia, for example, hypertension, diabetes, and emphysema. Further, many patients with chronic diseases have anemia but do not have the type of anemia under discussion. It is prudent to exclude iron, folate, and cobalamin...References1. WintrobeLeeBoggsBithellFoersterAthens MGDTJJ. Clinical Hematology. 8th ed. Philadelphia: Lea & Febiger; 1981. Google Scholar2. WilliamsBeutlerErslevLichtman WEAM. Hematology. 4th ed. New York: McGraw-Hill; 1990. Google Scholar3. Jandl J. Blood. Textbook of Hematology. Boston: Little, Brown & Company; 1987. Google Scholar4. HoffmanBenzFurieCohen REBH. Hematology. Basic Principles and Practice. New York: Churchill Livingstone; 1991. Google Scholar5. Hansen N. The anaemia of chronic disorders. A bag of unsolved questions. Scand J Haematol. 1983;31:397-402. CrossrefMedlineGoogle Scholar6. CartwrightLauritsenJonesMerrillWintrobe GMPIM. The anemia of infection. I. Hypoferremia, hypercupremia, and alterations in porphyrin metabolism in patients. J Clin Invest. 1946; 25:65-80. CrossrefGoogle Scholar7. BushAshenbruckerCartwrightWintrobe JHGM. The anemia of infection. 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J Exp Med. 1988;167:1211-27. CrossrefMedlineGoogle Scholar19. DinarelloCannonWolffBernheimBeutlerCerami CJSHBA. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986; 163:1433-50. CrossrefMedlineGoogle Scholar20. DeGowinReedHussev RWD. The significance of anemia in cancer patients anticipating radiotherapy [Abstract]. Clin Res. 1990;38:821A. Google Scholar21. JacobsJonesRickettsBulbrookWang ABCRD. Serum ferritin concentration in early breast cancer. Br J Cancer. 1976;34:286-90. CrossrefMedlineGoogle Scholar22. AderkaFisherLevoHoltmannHahnWallach DSYHTD. Cachectin/tumour-necrosis-factor production by cancer patients [Letter]. Lancet. 1985;2:1190. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Robert F. 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