The acetoacetyl group, an amino protective group of potential use in peptide synthesis
1965; Elsevier BV; Volume: 6; Issue: 10 Linguagem: Inglês
10.1016/s0040-4039(00)90004-2
ISSN1873-3581
AutoresFerruccio D’Angeli, Fernando Filira, Ernesto Scoffone,
Tópico(s)Chemical Synthesis and Analysis
ResumoThe use of the N-acetoacetyl protecting group for N-terminal cysteine residue enabled creation of an efficient and mild one-pot native chemical ligation/SEA ligation sequence giving access to large cyclic peptides.
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