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BIBTEX RIS

Leptin-Replacement Therapy for Lipodystrophy

2002; Massachusetts Medical Society; Volume: 346; Issue: 8 Linguagem: Inglês

10.1056/nejmoa012437

ISSN

1533-4406

Autores

Elif A. Oral, Vinaya Simha, Elaine Ruiz, Alexa Andewelt, Ahalya Premkumar, P. G. Snell, A. Wagner, Alex M. DePaoli, Marc L. Reitman, Simeon I. Taylor, Phillip Görden, Abhimanyu Garg,

Tópico(s)

Adipose Tissue and Metabolism

Resumo

The adipocyte hormone leptin is important in regulating energy homeostasis. Since severe lipodystrophy is associated with leptin deficiency, insulin resistance, hypertriglyceridemia, and hepatic steatosis, we assessed whether leptin replacement would ameliorate this condition.

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