Voltar
Artigo Revisado por pares
BIBTEX RIS

An SAR study for the non-peptide substance P receptor (NK1) antagonist, CP-96,345.

1992; Elsevier BV; Volume: 2; Issue: 6 Linguagem: Inglês

10.1016/s0960-894x(01)81197-5

ISSN

1464-3405

Autores

William Howson, Julie Hodgson, Reg Richardson, Lesley Walton, Steve Guard, Keith J. Watling,

Tópico(s)

Nitric Oxide and Endothelin Effects

Resumo

Results from an SAR study around the novel, non-peptide substance P receptor NK1 antagonist, (±)CP-96,345 (1) are described. The importance of the 2° nitrogen and the aromatic moieties are clarified.

Referência(s)