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A suplementação de L-carnitina não promove alterações na taxa metabólica de repouso e na utilização dos substratos energéticos em indivíduos ativos

2010; Editora da Universidade de São Paulo; Volume: 54; Issue: 1 Linguagem: Inglês

10.1590/s0004-27302010000100007

ISSN

1677-9487

Autores

Christianne de Faria Coelho‐Ravagnani, João Felipe Mota, Fabrício César de Paula Ravagnani, Roberto Carlos Burini,

Tópico(s)

Diet and metabolism studies

Resumo

To investigate the effects of L-carnitine supplementation, over thirty days, on the resting metabolic rate (RMR) and oxidation of free fatty acids (FFA) under rested or exercised conditions.Twenty-one overweight active volunteers (40 to 58 years old) were randomized into two groups: supplemented (GS; N = 11; 1,8 g/day of L-carnitine) or placebo (GP; N = 10; maltodextrin). Caloric intake, anthropometry, RMR, VO(2max), respiratory exchange ratio and plasma FFA were measured.No significant changes were found in the caloric intake (-244,66 vs. -126,00 kcal/day), body composition (-0.07 vs. -0.17 kg/m(2)), RMR (0.06 vs. -0.02 kcal/day), respiratory exchange ratio at rest (3.69 vs. -1.01) and exercise (0.01 vs. -0.01) or VO(2max) (0.50 vs. 1.25 mL/kg/min) between GS and GP. Plasma FFA levels were increased under resting conditions only in the GP group (0.27), but no significant changes were observed before or after physical activity in any of the groups.Supplementation with L-carnitine caused no changes in the variables analyzed in this study.

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