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Presumed Congenital Ocular Toxoplasmosis in Two Successive Siblings

1999; Karger Publishers; Volume: 213; Issue: 5 Linguagem: Inglês

10.1159/000027446

1423-0267

Ioannis D. Ladas, Charalampos Livir Rallatos, Christina S. Kanaki, Alexandros Damanakis, Panayotis Zafirakis, Gerasimos Livir Rallatos,

Herpesvirus Infections and Treatments

We present the cases of 2 consecutive siblings with bilateral macular lesions, for which there is strong clinical and laboratory evidence supporting the diagnosis of congenital ocular toxoplasmosis. These cases raise the possibility of maternal parasitemia during <i>Toxoplasma gondii</i> reinfection, leading to transmission to the fetus and congenital ocular toxoplasmosis despite prior immunity and lack of an immune disturbance in the mother.