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Membrane receptors for steroid hormones: Signal transduction and physiological significance

2002; Wiley; Volume: 88; Issue: 3 Linguagem: Inglês

10.1002/jcb.10409

1097-4644

Ilka Nemere, Richard J. Pietras, P F Blackmore,

Lipid Membrane Structure and Behavior

Abstract Membrane receptors for steroid hormones affect signaling pathways that modulate nuclear function, influence neuronal activity, ion flow, and the circulatory system. Indeed, ‘new’ steroid hormones have been identified by their interaction with membrane‐initiated signaling systems. A brief summary of the FASEB Summer Research Conference devoted to these topics is presented in this mini‐review. In addition, attendees of the meeting propose introduction of the following terminology: membrane‐initiated steroid signaling (MISS) and nuclear‐initiated steroid signaling (NISS) to replace more inaccurate terms in current use. © 2002 Wiley‐Liss, Inc.