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Cryptococcus gattii molecular type VGII as agent of meningitis in a healthy child in Rio de Janeiro, Brazil: report of an autochthonous case

2010; Brazilian Society of Tropical Medicine; Volume: 43; Issue: 6 Linguagem: Inglês

10.1590/s0037-86822010000600032

1678-9849

Vítor Laerte Pinto, Marcos Vinícius da Silva Pone, Sheila Moura Pone, J M Campos, José Roberto Garrido, Ana Cláudia Mamede Wiering de Barros, Luciana Trilles, Gláucia Gonçalves Barbosa, Bernardina Penarrieta Morales, Cláudia de Carvalho Falci Bezerra, Márcia dos Santos Lazéra,

Nail Diseases and Treatments

Cryptococcus gattii causes meningoencephalitis in immunocompetent hosts, occurring endemically in some tropical and subtropical regions. Recently, this fungus was involved in an outbreak in Vancouver Island and British Columbia (Canada). In this temperate region, the VGII type is predominant. The paper describes an autochthonous case of meningoencephalitis by C. gattii VGII in a previously health child in Rio de Janeiro, considered nonendemic region of Brazil. The fungus was identified by biochemical tests and the molecular type was determined by URA5-RFLP. The present report highlights the need for clinical vigilance for primary cryptococcal meningitis in nonendemic areas.