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Oral Ulcers Produced by Mycophenolate Mofetil in Two Liver Transplant Patients

2007; Elsevier BV; Volume: 39; Issue: 3 Linguagem: Inglês

10.1016/j.transproceed.2006.12.028

1873-2623

J. Naranjo, Jaime Poníachik, D. Cisco, Jorge Contreras, Danny Oksenberg, José Miguel Valera, Juan Carlos Díaz, Jorge Rojas, Gonzalo Cardemil, Sandy Iturra Mena, Jaime Castillo, G. Rencoret, J. Godoy, Jose Escobar, Jorge Rodríguez, Patricio Leyton, Alberto Fíca, Cássio Augusto Patrocínio Toledo,

Transplantation: Methods and Outcomes

Oral ulcers are a frequent problem in transplant medicine. It is important to consider infectious etiologies, exacerbated by the immunosuppressive treatment, but other etiologies are also possible, like adverse drug reactions. Mycophenolate mofetil (MMF) is an immunosuppressive medication that has been used in combination with calcineurin inhibitors and steroids. Reports of renal transplant patients with oral ulcers related to MMF have appeared lately and herein we have described 2 cases in liver transplant patients. Their oral ulcers resolved quickly after suspension of the medication. Our 2 cases in liver transplant patients represented a unique setting for this type of complication.