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BIBTEX RIS

Association of (CCTTT)10, a nitric oxide synthase 2 promoter polymorphism, with death due to acute lung injury

2008; BioMed Central; Volume: 12; Issue: Suppl 2 Linguagem: Inglês

10.1186/cc6684

ISSN

1466-609X

Autores

D Perez, C. Manzon, Jean-Christophe Navellou, Cyrille Patry, Gilles Capellier,

Tópico(s)

Respiratory Support and Mechanisms

Resumo

Nitric oxide via inducible nitric oxide synthase (NOS2) is believed to be a molecule central to the pathogenesis of acute lung injury (ALI). (CCTTT)n, a polymorphism within the NOS2 gene promoter, has been associated with outcome in some pathologies. The study objective was to investigate the frequency of the (CCTTT)n alleles in patients with ALI and to determine whether their occurrence affects the outcome of ALI.

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