Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment
1990; Oxford University Press; Volume: 42; Issue: 3 Linguagem: Inglês
10.1111/j.2042-7158.1990.tb05384.x
ISSN2042-7158
AutoresAntoni Gawron, Grzegorz Górski, Kazimierz Głowniak,
Tópico(s)Mycotoxins in Agriculture and Food
ResumoThe effect of 8-methoxypsoralen on human blood mononuclear cells cultured in darkness has been examined. 8-Methoxypsoralen (1 microgram mL-1, 4.6 microM) added to (phytohaemagglutinin-stimulated cells induced a two-fold increase in the number of mitoses. The number of blastic cells also increased. There was no effect on the formation of micronuclei and there was no chromosomal breakage.
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