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Cell cycle analysis in the mouse egg-cylinder

1971; Elsevier BV; Volume: 64; Issue: 2 Linguagem: Inglês

10.1016/0014-4827(71)90084-x

1090-2422

Davor Solter, N. Škreb, Ivan Damjanov,

Pluripotent Stem Cells Research

The cell cycle and its phases in the ectoderm and mesoderm of a seven-day-old mouse embryo was investigated by means of autoradiography. It was found that the duration of the total cell cycle for ectoderm is 6.25 h, G1 phase lasted 0.25 h, S phase 4 h, G2 0.5 h and mitosis 1.5 h. The corresponding values for mesoderm were: cell cycle 7.5 h, G1 phase 0.7 h, S phase 5 h, G2 0.5 h and mitosis 1.3 h. Comparison of the duration of the cell cycle and its phases, particularly the duration of S phase, points to the difference existing between the ectoderm and mesoderm at the moment of mesoderm formation.