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BIBTEX RIS

Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease

2009; Elsevier BV; Volume: 11; Issue: 13 Linguagem: Inglês

10.1016/j.micinf.2009.07.011

1769-714X

Cláudio Romero Farias Marinho, Luis N. Nuñez-Apaza, Karina Ramalho Bortoluci, André Luís Bombeiro, Daniella Zanetti Bucci, Marcos Grisotto, Luiz Roberto Sardinha, Christian E. Jorquera, Sérgio A. Lira, Maria Regina D’Império Lima, José María Álvarez,

Parasites and Host Interactions

The physiopathology of Chagas' disease has been largely defined in murine infections with virulent strains which partially represent parasite diversity. This report reviews our studies with Sylvio X10/4 parasites, a Trypanosoma cruzi clone that induces no acute phase but in C3H/He mice leads to chronic myocarditis resembling the human disease.