Produção Nacional
Revisado por pares
Effects ofMomordica charantiaL. on the Blood Rheological Properties in Diabetic Patients
2014; Hindawi Publishing Corporation; Volume: 2014; Linguagem: Inglês
10.1155/2014/840379
ISSN2314-6141
AutoresEduardo Luzía França, Elton Brito Ribeiro, Edson Fredulin Scherer, D. Cantarini, Rafael Souza Pessôa, Fernando Luzía França, Adenilda Cristina Honório‐França,
Tópico(s)Ginkgo biloba and Cashew Applications
ResumoAn evaluation of the rheological properties and the effects of Momordica. charantia L. (M. charantia) nanoparticles and polyethylene glycol (PEG) microspheres adsorbed with M. charantia nanoparticles on the blood of hyperglycemic patients is presented. Blood samples were collected according to glycemic status: normoglycemic (N = 56) and hyperglycemic (N = 26). General and hematological characteristics were determined. Blood rheological parameters were determined at room temperature and under a temperature scan. We determined the effects on whole blood viscosity of treatment with an extract of M. charantia, PEG, or PEG microspheres adsorbed with plant extract. The viscosity of the blood of hyperglycemic patients is greater than that of normoglycemic patients. Nanoparticles of M. charantia extracts lowered blood viscosity at equivalent rates in normo- and hyperglycemic individuals. PEG microspheres did not reduce blood viscosity in hyperglycemic individuals. However, PEG microspheres adsorbed with nanofraction extracts of M. charantia reduced blood viscosity. These data suggest that the effects of diabetes on the viscosity of the blood should be considered. The use of a nanoparticles extract of M. charantia and its adsorption on PEG microspheres may represent an alternative for the control and treatment of blood disorders in diabetic patients.
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