Immunosuppressive Activity of Seminal Plasma and Pregnancy-Associated Plasma Protein-A (PAPP-A) in Men
1983; Taylor & Francis; Volume: 10; Issue: 2 Linguagem: Inglês
10.3109/01485018308987562
ISSN1521-0375
AutoresRémy C. Martin-Du-Pan, P. Bischof, B Bourrit, K Lauber, J.P. Girard, Walter Herrmann,
Tópico(s)Xenotransplantation and immune response
ResumoAbstractPregnancy-associated plasma protein-A (PAPP-A) and inhibition of phytohemagglutinin (PHA)-induced lymphocyte transformation were measured in 51 seminal plasma samples obtained from oligozoospermic (n = 22), normospermic (n = 22), and vasectomized men (n = 7). In nonvasectomized men, PAPP-A significantly correlated with the percentage inhibition of lymphocyte transformation. The possibility of PAPP-A being an immunosuppressive principle of human seminal plasma is discussed.Key Words: PAPP-ASeminal plasmaImmunosuppressionOligozoospermiaVasectomy.
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