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Nail pigmentation caused by hydroxyurea: Report of 9 cases

2002; Elsevier BV; Volume: 47; Issue: 1 Linguagem: Inglês

10.1067/mjd.2002.120910

1097-6787

Nicola Aste, Giuseppe Fumo, Franca Contu, N. Aste, P. Biggio,

Dermatological diseases and infestations

We report a series of 9 patients, 6 men and 3 women, who presented nail hyperpigmentation arising between 6 and 24 months from the start of hydroxyurea therapy. The most commonly observed clinical pattern was that of longitudinal melanonychia. In only 1 patient, who was affected in all 20 nails, we observed longitudinal melanonychia, diffuse melanonychia, and hyperpigmentation of the skin.