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Normobaric Measurement of Arterial Oxygen Tension in Subjects Exposed to Hyperbaric Oxygen

1992; Elsevier BV; Volume: 102; Issue: 4 Linguagem: Inglês

10.1378/chest.102.4.1175

1931-3543

Lindell K. Weaver, Steve Howe,

Non-Invasive Vital Sign Monitoring

This study demonstrates the ability of an automated blood gas analyzer (Radiometer ABL 330) operated at atmospheric pressure to measure the arterial oxygen tension (PaO2) of ten healthy volunteers exposed to hyperbaric oxygen (HBO2) up to 3.0 atmospheres absolute. Arterial blood samples were aspirated from subjects compressed in a single-person hyperbaric chamber and were analyzed immediately in the blood gas analyzer. The subjects' values for PaO2 correlated with the calculated alveolar O2 tension (PAO2) (measured PaO2 = 0.827×PAO2 − 15.1) (r 2 Myers RA Functional hyperbaric chamber facilities: summary of questionnaires compiled by Maryland Institute of Emergency Medical Services (MIEMSS). MIEMSS, (Jan), Baltimore1988: 1-16 Google Scholar = 0.97). Tonometric experiments indicated a difference between saline and blood PO2 measurements. We therefore derived a correction factor for blood measurements (corrected PaO2 = 0.908 × PAO2 − 52.4) (r 2 Myers RA Functional hyperbaric chamber facilities: summary of questionnaires compiled by Maryland Institute of Emergency Medical Services (MIEMSS). MIEMSS, (Jan), Baltimore1988: 1-16 Google Scholar = 0.98). These results compared favorably with PaO2 measurements made with blood gas analyzers calibrated inside walk-in hyperbaric chambers. We conclude that the PaO2 of normal subjects exposed to HBO2 can be measured accurately at atmospheric pressure with this automated blood gas analyzer. Prior to this study, hyperbaric PaO2 measurements could only be performed within walk-in chambers. Our observations generalize the normobaric measurement of hyperbaric PaO2 to patients treated in single-person and walk-in chambers. This study demonstrates the ability of an automated blood gas analyzer (Radiometer ABL 330) operated at atmospheric pressure to measure the arterial oxygen tension (PaO2) of ten healthy volunteers exposed to hyperbaric oxygen (HBO2) up to 3.0 atmospheres absolute. Arterial blood samples were aspirated from subjects compressed in a single-person hyperbaric chamber and were analyzed immediately in the blood gas analyzer. The subjects' values for PaO2 correlated with the calculated alveolar O2 tension (PAO2) (measured PaO2 = 0.827×PAO2 − 15.1) (r 2 Myers RA Functional hyperbaric chamber facilities: summary of questionnaires compiled by Maryland Institute of Emergency Medical Services (MIEMSS). MIEMSS, (Jan), Baltimore1988: 1-16 Google Scholar = 0.97). Tonometric experiments indicated a difference between saline and blood PO2 measurements. We therefore derived a correction factor for blood measurements (corrected PaO2 = 0.908 × PAO2 − 52.4) (r 2 Myers RA Functional hyperbaric chamber facilities: summary of questionnaires compiled by Maryland Institute of Emergency Medical Services (MIEMSS). MIEMSS, (Jan), Baltimore1988: 1-16 Google Scholar = 0.98). These results compared favorably with PaO2 measurements made with blood gas analyzers calibrated inside walk-in hyperbaric chambers. We conclude that the PaO2 of normal subjects exposed to HBO2 can be measured accurately at atmospheric pressure with this automated blood gas analyzer. Prior to this study, hyperbaric PaO2 measurements could only be performed within walk-in chambers. Our observations generalize the normobaric measurement of hyperbaric PaO2 to patients treated in single-person and walk-in chambers.