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Reducing Lung Injury during Neonatal Resuscitation of Preterm Infants

2008; Elsevier BV; Volume: 153; Issue: 6 Linguagem: Inglês

10.1016/j.jpeds.2008.08.016

1097-6833

Georg M. Schmölzer, Arjan B. te Pas, Peter G. Davis, Colin J. Morley,

Neuroscience of respiration and sleep

Neonatologists are familiar with the concept of ventilator-induced lung injury (VILI) 1 Attar M.A. Donn S.M. Mechanisms of ventilator-induced lung injury in premature infants. Semin Neonatol. 2002; 7 (5): 353-360 Abstract Full Text PDF PubMed Scopus (168) Google Scholar , 2 Jobe A.H. Ikegami M. Mechanisms initiating lung injury in the preterm. Early Hum Dev. 1998; 53: 81-94 Abstract Full Text Full Text PDF PubMed Scopus (368) Google Scholar and are increasingly careful in the neonatal intensive care unit (NICU) to apply positive-pressure ventilation (PPV) strategies that are gentle to the lungs. 3 Clark R.H. Gerstmann D.R. Jobe A.H. Moffitt S.T. Slutsky A.S. Yoder B.A. Lung injury in neonates: causes, strategies for prevention, and long-term consequences. J Pediatr. 2001; 139: 478-486 Abstract Full Text Full Text PDF PubMed Scopus (192) Google Scholar Although PPV also is commonly used in the delivery room (DR), clinicians appear less aware that the same gentle approach should be applied to reduce lung injury during the first few minutes of life.