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The Pseudomonas aeruginosa motR gene involved in regulation of bacterial motility

2000; Oxford University Press; Volume: 184; Issue: 1 Linguagem: Inglês

10.1111/j.1574-6968.2000.tb08990.x

1574-6968

Jesús Campos‐García, Rebeca Nájera, Laura Camarena, Gloria Soberà n-Chávez,

Biochemical and Structural Characterization

A mini-Tn5-Hg insertion mutant derived from Pseudomonas aeruginosa W51D (W51M1) was isolated in which mini-Tn5 insertion disrupted the motR gene showing that it forms part of the cluster involved in bacterial motility and chemotaxis. Characterization of the W51M1 motility behavior, and also of a PAO1 motR::mini-Tn5-Hg mutant, suggests that the product of the motR gene is a negative regulator of bacterial motility which controls the number of flagella per cell.