Cu2O acting as a robust catalyst in CuAAC reactions: water is the required medium
2011; Royal Society of Chemistry; Volume: 13; Issue: 3 Linguagem: Inglês
10.1039/c0gc00848f
ISSN1463-9270
AutoresKai Wang, Xihe Bi, Shuangxi Xing, Peiqiu Liao, Zhongxue Fang, Xianyu Meng, Qian Zhang, Qun Liu, Yu Ji,
Tópico(s)Nanomaterials for catalytic reactions
ResumoCu2O as the catalyst in water was found to be quite robust for the azide-alkyne cycloaddition (AAC) reaction, which was verified by a wide variety of applicable azides and alkynes. Water was proved to play an essential role because of a significant rate acceleration compared with reactions using organic solvents and conducted under neat conditions. The high catalytic performance of Cu2O/H2O system was further argued by decreasing the catalyst loading to ppm levels.
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