Neuropsychiatric Manifestations of Typhoid Fever in 959 Patients
1972; American Medical Association; Volume: 27; Issue: 1 Linguagem: Inglês
10.1001/archneur.1972.00490130009002
ISSN1538-3687
AutoresB. O. Osuntokun, O. Bademosi, K. Ogunremi, Sally Wright,
Tópico(s)Cerebral Palsy and Movement Disorders
ResumoThe neurospsychiatric manifestations of typhoid fever in 959 Nigerian patients included confusional states or delirium (57%), semicoma (2.6%), coma (1.0%), meningism (5%), meningitis (0.2%), convulsions (1.7%), generalized myoclonus (0.5%), focal neurological deficit— deafness, hemiplegia, infranuclear facial palsy— (0.5%), transient or evanescent parkinsonism (1.0%), symmetrical, usually transient, spasticity of all limbs (3.1%), and generalized hypotonicity (0.2%). Seven patients had symmetrical sensorimotor polyneuropathy without cytoalbuminological dissociation in cerebrospinal fluid, and three patients had a mononeuritis. One young man developed motor neuron disease two months after recovering from typhoid fever. In five patients (0.5%), the initial diagnosis was schizophrenia. Two developed schizophrenic psychoses, and two other patients suffered from temporary amnesia during convalescence.
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