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Evolution of maxillofacial brown tumors after parathyroidectomy in primary hyperparathyroidism

2008; Wiley; Volume: 30; Issue: 11 Linguagem: Inglês

10.1002/hed.20905

1097-0347

Jaime Alonso Reséndiz‐Colosia, Sergio Rodrı́guez-Cuevas, Rutilio Flores‐Díaz, Martín Hernández‐San Juan, José Francisco Gallegos‐Hernández, Sinhué Barroso‐Bravo, Fernando Gómez‐Acosta,

Oral and Maxillofacial Pathology

Abstract Background. Brown tumor occasionally affects the facial bones. Clinically, these lesions can be mistaken for a neoplasm. Opinions are divided on the course of management of the bony lesions once parathyroidectomy has been carried out. Methods. We treated 22 patients with primary hyperparathyroidism and osteitis fibrosa cystica and observed their clinical and biochemical recovery. Results. Fifteen patients (68.2%) had brown tumors in mandible, and 7 (31.8%) in maxilla. After parathyroidectomy, 21 patients had normal total serum calcium values. All brown tumors presented a spontaneous progressive regression; in 18cases, regression was total, with a mean time period of 10months. Two patients had partial regression after nearly 2years. Another 2 patients were lost to follow‐up. Conclusions. After successful parathyroid surgery, the bony lesions tended to regress spontaneously, either partially or completely. However, if the lesion is disfiguring or symptomatic, surgical excision may be indicated. © 2008 Wiley Periodicals, Inc. Head Neck, 2008