Enantioselective catalytic reduction of acetophenone with borane in the presence of cyclic α-amino acids and their corresponding β-amino alcohols
1994; Elsevier BV; Volume: 5; Issue: 2 Linguagem: Inglês
10.1016/s0957-4166(00)86168-6
ISSN1362-511X
AutoresThomas Mehler, W. Behnen, J. WILKEN, Jürgen Martens,
Tópico(s)Chemical Synthesis and Analysis
ResumoThe direct application of α-amino acids as chiral auxiliaries in the enantioselective catalytic reduction of acetophenone with borane in refluxing toluene has been investigated. A comparison with the corresponding β-amino alcohols as optically active catalysts is involved.
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