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Chemical Quantitation of Epinephrine and Norepinephrine in Thirteen Patients with Pheochromocytoma

1954; Lippincott Williams & Wilkins; Volume: 10; Issue: 5 Linguagem: Inglês

10.1161/01.cir.10.5.641

1524-4539

William M. Manger, Eunice V. Flock, Joseph Berkson, Jesse L. Bollman, Grace M. Roth, Edward J. Baldes, Martin Jacobs,

Drug-Induced Ocular Toxicity

HomeCirculationVol. 10, No. 5Chemical Quantitation of Epinephrine and Norepinephrine in Thirteen Patients with Pheochromocytoma Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBChemical Quantitation of Epinephrine and Norepinephrine in Thirteen Patients with Pheochromocytoma WILLIAM M. MANGER, M.D., EUNICE V. FLOCK, PH.D., JOSEPH BERKSON, M.D., JESSE L. BOLLMAN, M.D., GRACE M. ROTH, PH.D., EDWARD J. BALDES, PH.D. and MARTIN JACOBS WILLIAM M. MANGERWILLIAM M. MANGER From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. , EUNICE V. FLOCKEUNICE V. FLOCK From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. , JOSEPH BERKSONJOSEPH BERKSON From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. , JESSE L. BOLLMANJESSE L. BOLLMAN From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. , GRACE M. ROTHGRACE M. ROTH From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. , EDWARD J. BALDESEDWARD J. BALDES From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. and MARTIN JACOBSMARTIN JACOBS From the Mayo Clinic and Mayo Foundation, Rochester, Minn. The Mayo Foundation is a part of the Graduate School of the University of Minnesota. Originally published1 Nov 1954https://doi.org/10.1161/01.CIR.10.5.641Circulation. 1954;10:641–652AbstractFluorescent quantitation of epinephrine and norepinephrine in plasma of patients suspected of having pheochromocytomas is of considerable diagnostic value. The concentrations of these pressor amines in normal subjects, patients with various diseases with and without hypertension, and 13 patients with pheochromocytomas are reported. In all patients with pheochromocytomas and sustained hypertension the concentrations of pressor amines were significantly elevated. However, in patients with paroxysmal hypertension secondary to pheochromocytomas the pressor amine concentrations may be unelevated when the blood pressures are normal. In this latter group provocative tests with intravenous histamine are indicated to induce hypertension prior to quantitating pressor amines. 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November 1, 1954Vol 10, Issue 5 Advertisement Article InformationMetrics © 1954 American Heart Association, Inc.https://doi.org/10.1161/01.CIR.10.5.641 Originally publishedNovember 1, 1954 PDF download Advertisement