
Approach to and Treatment of Goiters
2012; Elsevier BV; Volume: 96; Issue: 2 Linguagem: Inglês
10.1016/j.mcna.2012.01.010
ISSN1557-9859
AutoresGeraldo Medeiros‐Neto, R. Y. A. Camargo, Eduardo Tomimori,
Tópico(s)Thyroid and Parathyroid Surgery
ResumoThe main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L -thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects.
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