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BIBTEX RIS

Effects of sinvastatin in prevention of vasospasm in nontraumatic subarachnoid hemorrhage: preliminary data

2012; BioMed Central; Volume: 16; Issue: S1 Linguagem: Inglês

10.1186/cc10922

1466-609X

S Macedo, Valéria Magalhães Aguiar, PF Rosa, IT Ladeia, YK Castro, Leandro A. Ferreira, DR De Melo, LG Rezende,

Acute Ischemic Stroke Management

Some trials have shown that statins in the acute phase of aSAH reduce the incidence, morbidity and mortality of cerebral vasospasm. Independent of their cholesterol-lowering effect, statins have multiple biological properties, including downregulating inflammation and upregulating endothelial NO synthase. The purpose of this study is to evaluate the potential of sinvastatin (SVT) as prevention against vasospasm.