Verapamil vs Quinine in Recumbent Nocturnal Leg Cramps in the Elderly
1990; American Medical Association; Volume: 150; Issue: 4 Linguagem: Inglês
10.1001/archinte.1990.00390160160052
ISSN1538-3679
Autores Tópico(s)Pharmacology and Obesity Treatment
Resumothe Editor.—I read with interest the article entitled Verapamil vs Quinine in Recumbent Nocturnal Leg Cramps in the Elderly by Baltodano et al that appeared in the September 1988 issue of theArchives.1 The third paragraph of the article starts off with the statement, To date, the most effective treatment (for treatment of recumbent nocturnal leg cramps in the elderly) has been quinine. The source of this statement wasMedical Letters Drug Therapy.2The article then goes on to state that, in patients whose nocturnal leg cramps do not respond to quinine, use of verapamil (120 mg) at bedtime was beneficial. I was surprised that no mention was made of the use of diphenhydramine hydrochloride (Benadryl) (50 mg) at bedtime in the treatment of nocturnal leg cramps. I have been using this drug as a first-line treatment for nocturnal leg cramps with great success. If the
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