Quantitative EEG in never-treated schizophrenic patients
1995; Elsevier BV; Volume: 38; Issue: 5 Linguagem: Inglês
10.1016/0006-3223(95)00300-6
ISSN1873-2402
AutoresMasao Omori, Yoshifumi Koshino, Tetsuhito Murata, I. Murata, Masashi Nishio, Kazumasa Sakamoto, Tan Horie, Kiminori Isaki,
Tópico(s)EEG and Brain-Computer Interfaces
ResumoTo clarify whether patients with schizophrenia still show EEG slowing in the absence of psychopharmacological treatment, EEG was analyzed in 20 acute never-treated schizophrenics and 20 age-matched healthy controls using the computerized wave-form recognition method. Compared to controls, schizophrenics had more fast theta (6-8 Hz) and slow alpha (8-9 Hz) activity, and less fast alpha activity (9-13 Hz). The average EEG frequency at O1 correlated negatively with total and positive symptom scores on the BPRS in the schizophrenic group. These findings confirm that the frequency of alpha rhythm is slowed in schizophrenia and that this slowing is possibly related to the expression of psychopathology in this disorder.
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