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Vortex chamber for in situ recovery of the antibiotic myxovirescin A in continuous cultivation

1987; Wiley; Volume: 29; Issue: 2 Linguagem: Inglês

10.1002/bit.260290212

1097-0290

V. Hecht, Jürgen Vorlop, H. Kalbitz, Klaus Gerth, Jürgen Lehmann,

Microbial infections and disease research

Abstract A vortex chamber for continuous adsorption of the antibiotic Myxovirescin A on XAD resins was developed. In this paper the design and use of the vortex chamber in an external bypass of a continuous process is described. Compared with the normal continuous process, the specific production rate of the antibiotic is four to five times higher when the antibiotic is continuously adsorbed. A semicontinuous process could be performed by using two chambers for adsorption and regeneration alternatively.