High performance method for O-methylation of phenol with dimethyl carbonate
2003; Elsevier BV; Volume: 241; Issue: 1-2 Linguagem: Inglês
10.1016/s0926-860x(02)00467-2
ISSN1873-3875
AutoresSamedy Ouk, Sophie Thiébaud‐Roux, Elisabeth Borredon, Pierre Le Gars,
Tópico(s)Chemical Synthesis and Reactions
ResumoThe O-methylation of phenols, including the sterically hindered phenols, with dimethyl carbonate (DMC) under mild conditions of temperature and pressure was described. The reaction was carried out in the presence of tetrabutylammonium bromide (TBAB), in a semi-continuous process. Aryl methyl ethers were rapidly and selectively obtained in good yields.
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