Portal de Periódicos da CAPES

Propargyl Glycosides as Stable Glycosyl Donors: Anomeric Activation and Glycoside Syntheses

2006; American Chemical Society; Volume: 128; Issue: 30 Linguagem: Inglês

10.1021/ja062425c

1943-2984

Srinivas Hotha, Sudhir Kashyap,

Synthetic Organic Chemistry Methods

The advantages of stable glycosyl donors for saccharide coupling are many, and we describe herein the utility of propargyl glycosides for anomeric activation and glycoside synthesis exploiting the alkynophilicity of AuCl3. Various aglycones were reacted with propargyl glycosides, resulting in the formation of an α,β-mixture of glycosides and disaccharides in good yields.