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Oral sildenafil for the treatment of Raynaud's phenomenon and digital ulcers secondary to systemic sclerosis

2005; BMJ; Volume: 64; Issue: 9 Linguagem: Inglês

10.1136/ard.2004.034488

1468-2060

James Gore,

Connective Tissue Growth Factor Research

This case illustrates the usefulness of a therapeutic trial of colchicine monitored objectively by frequent acute phase protein measurements in patients with undiagnosed periodic fever syndromes.It also raises the possibility that a low threshold for analysing the FMF gene might disclose a wider spectrum of associated disease.