Produção Nacional
Revisado por pares
Prenylated flavonoids from Deguelia hatschbachii and their systematic significance in Deguelia
2001; Elsevier BV; Volume: 57; Issue: 1 Linguagem: Inglês
10.1016/s0031-9422(00)00509-4
ISSN1873-3700
AutoresAderbal F. Magalhães, Ana Maria G.A. Tozzi, Eva G. Magalhães, Valéria Regina de Souza Moraes,
Tópico(s)Essential Oils and Antimicrobial Activity
ResumoChemical investigation of dichloromethane and petrol extracts from the roots of D. hatschbachii A. M. G. Azevedo furnished thirteen compounds from which five are described for the first time and their structures were determined to be 3-(4′-hydroxyphenyl)-5-methoxy-6-(3,3-dimethylallyl)-2′′,2′′-dimethylchromene-(5′′,6′′:8,7)-3-(propyl-2-one)-4H-1-benzo-2,3-dihydropyran-2,4-dione; 6,4′-dihydroxy-3-(3,3-dimethylallyl)-2′′,2′′-dimethylchromene (5′′,6′′:5,4)-2-methoxy deoxybenzoin; 6,4′-dihydroxy-3-(3,3-dimethylallyl)-2′′,2′′-dimethylchromene (5′′,6′′:5,4)-2-methoxy-8-(propyl-2-one) deoxybenzoin; 6-(3,3-dimethylallyl)-2′′,2′′-dimethylchromene (5′′,6′′:4,5)-4′-hydroxy-3-methoxy stilbene and 3,5-dimethoxy-4′-hydroxy-4-(3,3-dimethylallyl) stilbene by spectral analysis (UV, IR, MS and 1D- and 2D- NMR experiments). The root extracts and some isolated compounds were bioactive, as revealed by bioautography and brine shrimp lethality assays.
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