Ergotamine Use in Pregnancy
1996; Wiley; Volume: 36; Issue: 2 Linguagem: Inglês
10.1111/j.1479-828x.1996.tb03275.x
ISSN1479-828X
Autores Tópico(s)Grief, Bereavement, and Mental Health
ResumoEDITORIAL COMMENT: We accepted this short report for publication to warn readers that ergotamine may cause acute fetal hypoxia. Although prescribing information lists pregnancy as a contraindication, there is still a belief that ergotamine can be used in pregnancy. The mechanism of injury of the fetus is not clear‐cut. The use of ergotamine was associated with more than just the fetal brain becoming hypoxic: the cardiotocograph shows features of myocardial ischaemia as well. The fact that the infant was stillborn also suggests myocardial injury, so that isolated cerebral vasospasm seems unlikely. It is of interest that meconium was not passed. Both this case and that described in reference 4 indicate that ergotamine may cause uterine contractions as well as vasospasm.
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