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Comparison of virucidal activity of alcohol-based hand sanitizers versus antimicrobial hand soaps in vitro and in vivo

2012; Elsevier BV; Volume: 82; Issue: 4 Linguagem: Inglês

10.1016/j.jhin.2012.08.005

1532-2939

Jochen Steinmann, Dajana Paulmann, Benedikt Becker, B. Bischoff, Eike Steinmann, Jörg Steinmann,

Clostridium difficile and Clostridium perfringens research

Three ethanol-based sanitizers were compared with three antimicrobial liquid soaps for their efficacy to inactivate polio-, adeno-, vaccinia- and bovine viral diarrhoea virus (BVDV) as well as feline calicivirus (FCV) and murine norovirus (MNV) as surrogates for human norovirus in a suspension test. Additionally, sanitizers and soaps were examined against MNV in a modified fingerpad method. All sanitizers sufficiently inactivated the test viruses in the suspension test whereas two soaps were active only against vaccinia virus and BVDV. In the modified fingerpad test a povidone-iodine-containing soap was superior to the sanitizers whereas the other two soaps showed no activity.