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Pyoderma gangrenosum in inflammatory bowel disease: The experience at Mater Health Services' Adult Hospital 1998–2009

2011; Oxford University Press; Volume: 5; Issue: 2 Linguagem: Inglês

10.1016/j.crohns.2010.10.006

1876-4479

Margit Polcz, Jennie Gu, Timothy H. Florin,

Inflammatory Bowel Disease

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis often associated with inflammatory bowel disease (IBD). The literature has suggested that PG-IBD is usually associated with ulcerative colitis.We reviewed the PG-IBD cases at the Mater Health Services' Adult Hospital in Brisbane between 1998 and 2009 through assessment of a comprehensive web database of IBD patients and verification of chart information of PG-IBD cases.PG-IBD at Mater was associated with clinically mild colonic IBD, with erythema nodosum, and with female sex. All PG-IBD responded eventually to increased immunomodulatory therapy.We discuss why PG-IBD is associated with clinically mild colonic IBD be it ulcerative colitis, Crohn's or indeterminate colitis.