Portal de Periódicos da CAPES

Comparison of compliance for colorectal cancer screening and surveillance by colonoscopy based on risk

2011; Elsevier BV; Volume: 13; Issue: 8 Linguagem: Inglês

10.1097/gim.0b013e3182180c71

1530-0366

David P. Taylor, Lisa Cannon‐Albright, Carol Sweeney, Marc S. Williams, Peter J. Haug, Joyce A. Mitchell, Randall W. Burt,

Genetic factors in colorectal cancer

Abstract Purpose To compare colonoscopy screening/surveillance rates by level of risk for colorectal cancer based on age, personal history of adenomatous polyps or colorectal cancer, or family history of colorectal cancer. Methods Participants were aged 30–90 years, were seen within 5 years at Intermountain Healthcare, and had family history in the Utah Population Database. Colonoscopy rates were measured for those with/without risk factors. Results Among those aged 60–69 years, 48.4% had colonoscopy in the last 10 years, with rates declining after age 70 years. Percentages of those having had a colonoscopy in the last 10 years generally increased by risk level from 38.5% in those with a familial relative risk 3.0. Compared with those with no family history, the odds ratio for being screened according to guidelines was higher for those with one first-degree relative diagnosed with colorectal cancer ≥ 60 years or two affected second-degree relatives (1.54, 95% confidence interval: 1.46–1.61) than those with one affected first-degree relative diagnosed <60 years or ≥2 affected first-degree relatives (1.25, 95% confidence interval: 1.14–1.37). Conclusions Compliance with colonoscopy guidelines was higher for those with familial risk but did not correspond with the degree of risk.