7-Oxo-2-thia-1-azabicyclo[3.2.0]hept-3-ene, a revised structure for penems synthesized via oxidative addition mediated by copper(I)
1980; Elsevier BV; Volume: 21; Issue: 7 Linguagem: Inglês
10.1016/s0040-4039(01)85573-8
ISSN1873-3581
AutoresS. OIDA, Akira Yoshida, Teruo Hayashi, Eiji Nakayama, Sadao Sato, Eiji Ohki,
Tópico(s)Antibiotics Pharmacokinetics and Efficacy
ResumoAbstract The structure for the fused β-lactam obtained by treatment of the secolactam 3 with base in the presence of Cu(I)-ion is not the penem 1 (R=CH 3 ), but the isopenem 4 on the basis of X-ray analysis.
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