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A meta-analysis of sublingual allergen immunotherapy and pharmacotherapy in pollen-induced seasonal allergic rhinoconjunctivitis

2014; BioMed Central; Volume: 12; Issue: 1 Linguagem: Inglês

10.1186/1741-7015-12-71

1741-7015

Philippe Devillier, Jean‐François Dreyfus, Pascal Demoly, Moisés A. Calderón,

Dermatology and Skin Diseases

The capacity of sublingual allergen immunotherapy (SLIT) to provide effective symptom relief in pollen-induced seasonal allergic rhinitis is often questioned, despite evidence of clinical efficacy from meta-analyses and well-powered, double-blind, placebo-controlled randomized clinical trials. In the absence of direct, head-to-head, comparative trials of SLIT and symptomatic medication, only indirect comparisons are possible.