Our Knowledge of Vaccination and Revaccination as Preventive of Small-Pox. Part II
1850; BMJ; Volume: s2-2; Issue: 24 Linguagem: Inglês
10.1136/bmj.s2-2.24.1134
ISSN0959-8138
Autores Tópico(s)Viral gastroenteritis research and epidemiology
ResumoAN argument, derived from the alleged composition of the lymph, might have been advanced, in confirmation of the identity of the Vaccine and Variolous Diseases, but it has been designedly omitted as prema- ture, until the existence of the phenomena, said to be revealed by the microscope, shall have been confirmed by repeated and careful examina- tion.This part of the subject would, however, be incomplete, without a passing notice of the very interesting observations contributed by Mr. E. Oke Spooner, to the July number (1850) of the Pronincial Medical and Surgical Joumal, p. 367.The purport of that gentleman's views will, however, be best explained in his own words." If we examine the Cow-pock and the Small-pox microscopically, as I have done very carefully in every stage, we find that the essential character consists of a number of minute cells, not exceeding the 10,000th part of an inch in diameter, being about one-fourth smaller than the globules-of the blood, containing within their circumference many still more minute nuclei, and presenting beyond their circum- ference bud-like cells, of the same size and character as those contained in the circle.They exactly resemble in everything, except the size, the globules of the yeast plant, the Torula cerevisie."In conclusion, the leading phenomena of the three forms of Small- pox may be thus grouped with reference to their identity.NATURAL SALL-POX.-General symptoms usually Primary fever, may be tphoid, more usually inflammatory, declining about the fifth day.Eruption of papull on the third day, completed on the fourth; papula gener- ally numerous.Papule vesicular on the fifth day, and containing pellucid lymph.INOCULATED BXALL-POX.Usuay mild.No primary fever.Minute papul on the third day-gerally few in number, and sometimes confined to the puncture or its locality.Vesicular, with clear lymph on the fourth day.VACCnEB SMALL-POX.Almost invariably mild.No primary fever.minute i dpapua on the fourth day; the ermption, with rae ex- ceptionts, fined to the pomnt of operation.VesRle on the fifth day, containing clearlymph.Vesicles depressed in the Vesicles depressed in the Vesicle depressed in the centre. centre.centre.Rednes around the are-Pain of axilla about the Pain of the arm, and o ta,te papulze a aminga sixth day; areola on the sometimes of the axilla, deePer hue, as the pustules ninth or tenth day.Fever, about the eighth or ninth ripen.sometimes severe, about day. the eighth day.Vesicles asume the form By the tenth day, the Areola on the eighth of distinct opaque pustules, primary pustule is full of or ninth day.Fever either spherical or acumin.matter.slight, sometimes inap.
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